Article
Robustness: mechanisms and consequences.
Trends in genetics : TIG - 1 Sept 2009
Masel Joanna, Siegal Mark L
Abstract excerpt
Biological systems are robust to perturbation by mutations and environmental fluctuations. New data are shedding light on the biochemical and network-level mechanisms responsible for robustness. Robustness to mutation might have evolved as an adaptation to reduce the effect of mutations, as a congruent byproduct of adaptive robustness to environmental variation, or as an intrinsic property of biological systems...
Topics
- Adaptation, Biological
- Animals
- Evolution, Molecular
- Gene Expression
- Genetic Variation
- Mutation
