Article
Genetic redundancies and their evolutionary maintenance.
Advances in experimental medicine and biology - 1 Jan 2012
Zhang Jianzhi
Abstract excerpt
Genetic redundancy refers to the common phenomenon that deleting or mutating a gene from a genome has minimal or no impact on the phenotype or fitness of the organism because of functional compensation conferred by one or more other genes. Here I summarize studies of functional redundancies between duplicate genes and those among metabolic reactions that respectively represent genetic redundancies at the...
Topics
- Animals
- Biological Evolution
- Escherichia coli
- Genes, Duplicate
- Genetic Fitness
- Genome
- Humans
- Models, Genetic
- Phenotype
- Saccharomyces cerevisiae
