Article
Genetic redundancies and their evolutionary maintenance.
Advances in experimental medicine and biology - 1 Jan 2012
Zhang Jianzhi
Abstract excerpt
Genetic redundancy refers to the common phenomenon that deleting or mutating a gene from a genome has minimal or no impact on the phenotype or fitness of the organism because of functional compensation conferred by one or more other genes. Here I summarize studies of functional redundancies between duplicate genes and those among metabolic reactions that respectively represent genetic redundancies at the...
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