Article
Weight gain associated with the -759C/T polymorphism of the 5HT2C receptor and olanzapine.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2005
Ellingrod Vicki L, Perry Paul J, Ringold John C, Lund Brian C, Bever-Stille Kristy, Fleming Frank, Holman Timothy L, Miller Del
Abstract excerpt
BACKGROUND: Weight gain from atypical antipsychotic use has become a significant problem. Recent reports have liked the -759 polymorphism of the 5HT2C receptor and obesity as well as weight gain from chlorpromazine, risperidone, and clozapine. AIM: To determine associations between weight gain during olanzapine treatment and the -759C/T polymorphism of the 5HT2C receptor gene. METHODS: This study included 42...
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