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[Association of antipsychotic agent-induced weight gain with a polymorphism of the promotor region of the 5-HT2C receptor gene].

Zhonghua yi xue za zhi - 25 Aug 2002

Zhang Zhijun, Zhang Xiaobin, Yao Zhijian, Chen Jianfang, Sun Jing, Yao Hui, Hou Gang, Zhang Xinbao, Reynolds Gavin P

Abstract excerpt

OBJECTIVE: To determine whether 5-hydroxytryptamine 2C (5-HT2C) receptor gene 759C/T polymorphism influences the weight gain following antipsychotic agents (APS) treatment in patient with schizophrenia. METHODS: DNA was extracted from the peripheral blood of 117 Chinese first-episode patients of Han nationality with schizophrenia diagnosed according to CCMD-II-R criteria. PCR-RELP technique was used to analyse...

Topics

Adolescent
Adult
Antipsychotic Agents
Body Mass Index
DNA
Female
Gene Frequency
Genotype
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Polymorphism, Genetic

Promoter Regions, Genetic

Receptor, Serotonin, 5-HT2C

Receptors, Serotonin

Schizophrenia

Weight Gain

Source

Identifiers

PMID: 12425817

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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[Association of antipsychotic agent-induced weight gain with a polymorphism of the promotor region of the 5-HT2C receptor gene].PMID 12425817Read ↗

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