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Article

Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia.

The Journal of clinical psychiatry - 1 Aug 2012

Houston John P, Kohler Jared, Bishop Jeffrey R, Ellingrod Vicki L, Ostbye Katherine M, Zhao Fangyi, Conley Robert R, Poole Hoffmann Vicki, Fijal Bonnie A

Abstract excerpt

OBJECTIVE: Pharmacogenomic analyses of weight gain during treatment with second-generation antipsychotics have resulted in a number of associations with variants in ankyrin repeat and kinase domain containing 1 (ANKK1)/dopamine D2 receptor (DRD2) and serotonin 2C receptor (HTR2C) genes. These studies primarily assessed subjects with schizophrenia who had prior antipsychotic exposure that may have influenced the...

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Source

Identifiers

PMID: 22967772
DOI: 10.4088/JCP.11m06916

Genes

DRD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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