Article
Lack of association between the -759C/T polymorphism of the 5-HT2C receptor gene and olanzapine-induced weight gain among Korean schizophrenic patients.
Journal of clinical pharmacy and therapeutics - 1 Feb 2008
Park Y-M, Cho J-H, Kang S-G, Choi J-E, Lee S-H, Kim L, Lee H-J
Abstract excerpt
BACKGROUND: Weight gain can be an adverse effect of antipsychotics that significantly affects long-term health and treatment compliance. Many reports have suggested that the 5-HT2C receptor gene (HTR2C) is related to appetite and eating behaviours associated with body weight change. We hypothesized that there was a relationship between the HTR2C -759C/T polymorphism and olanzapine-induced weight gain. METHOD:...
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