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Article

Mutagenesis of N-terminal residues of feline foamy virus Gag reveals entirely distinct functions during capsid formation, particle assembly, Gag processing and budding.

Retrovirology - 22 Aug 2016

Liu Yang, Betts Matthew J, Lei Janet, Wei Guochao, Bao Qiuying, Kehl Timo, Russell Robert B, Löchelt Martin

Abstract excerpt

BACKGROUND: Foamy viruses (FVs) of the Spumaretrovirinae subfamily are distinct retroviruses, with many features of their molecular biology and replication strategy clearly different from those of the Orthoretroviruses, such as human immunodeficiency, murine leukemia, and human T cell lymphotropic viruses. The FV Gag N-terminal region is responsible for capsid formation and particle budding via interaction with...

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Identifiers

PMID: 27549192
DOI: 10.1186/s12977-016-0291-8
PMCID: PMC4994201

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Source receipt: pubmed, retrieved 7 Sept 2026.

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