Article
Longitudinal assessment of immune response and viral characteristics in HIV-infected patients with prolonged CD4(+)/viral load discordance.
AIDS research and human retroviruses - 1 Jan 2005
Kaplan Susan S, Ferrari Guido, Wrin Terri, Hellmann Nicholas S, Tomaras Georgia D, Gryszowka Victoria E, Fiscus Susan A, Weinhold Kent J, Hicks Charles B
Abstract excerpt
Although suppression of HIV-1 RNA below the limit of detection is associated with optimal outcomes, many patients can maintain or increase their CD4(+) count for prolonged time periods in the presence of persistent low-level viremia. We followed seven patients with prolonged (>5 years) discordant CD4(+)/viral load (VL) responses on protease inhibitor (PI)-based highly active antiretroviral therapy (HAART)...
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