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Article

Antiretroviral therapy suppressed participants with low CD4+ T-cell counts segregate according to opposite immunological phenotypes.

AIDS (London, England) - 24 Sept 2016

Pérez-Santiago Josué, Ouchi Dan, Urrea Victor, Carrillo Jorge, Cabrera Cecilia, Villà-Freixa Jordi, Puig Jordi, Paredes Roger, Negredo Eugènia, Clotet Bonaventura, Massanella Marta, Blanco Julià

Abstract excerpt

BACKGROUND: The failure to increase CD4 T-cell counts in some antiretroviral therapy suppressed participants (immunodiscordance) has been related to perturbed CD4 T-cell homeostasis and impacts clinical evolution. METHODS: We evaluated different definitions of immunodiscordance based on CD4 T-cell counts (cutoff) or CD4 T-cell increases from nadir value (ΔCD4) using supervised random forest classification of 74...

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Identifiers

PMID: 27427875
DOI: 10.1097/QAD.0000000000001205
PMCID: PMC5017266

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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