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Article

Allelic imbalance analysis using a single-nucleotide polymorphism microarray for the detection of bladder cancer recurrence.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Dec 2008

Coenen Marieke J H, Ploeg Martine, Schijvenaars Mascha M V A P, Cornel Erik B, Karthaus Herbert F M, Scheffer Hans, Witjes J Alfred, Franke Barbara, Kiemeney Lambertus A L M

Abstract excerpt

PURPOSE: Non-muscle-invasive bladder cancer is a frequently occurring cancer, with an extremely high recurrence risk. Recurrence detection is based on cytology and urethrocystoscopy. A previous study suggested that a single-nucleotide polymorphism (SNP) array may be effective for noninvasive detection of allelic imbalances in urine. We investigated whether this method is suitable to detect allelic imbalance as an...

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PMID: 19088036
DOI: 10.1158/1078-0432.CCR-08-1103

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