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Article

Comparison of TLR4 Genotype and TLR4 Pathway-Related Cytokines in Different Strains of Mice in Response to Pertussis Toxin Challenge.

Genes - 5 Nov 2024

Wei Jie, Wang Lichan, Wei Chen, Guang Jiaona, Wang Hong, Zhou Jiaqi, Li Huan, Ma Xiao, Yue Bingfei

Abstract excerpt

BACKGROUND: The genetic background of Toll-like receptor 4 (TLR4) proved to be important in the induction of immune protection against Bordetella pertussis infection in humans. Currently, the evaluation of the acellular pertussis (aP) vaccine depends largely on using different mouse strains, while the TLR4 genotype of different mouse strains in response to pertussis toxin (PT) is not carefully determined. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39596635
DOI: 10.3390/genes15111435
PMCID: PMC11593472

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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