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Article

Interleukin-6 -174G/C polymorphism and longevity: a follow-up study.

Mechanisms of ageing and development - 1 Mar 2005

Hurme M, Lehtimäki T, Jylhä M, Karhunen P J, Hervonen A

Abstract excerpt

Increased rate of inflammation has been observed to be associated with aging. This is manifested, e.g. as increased blood levels of proinflammatory cytokines, such as interleukin-6 (IL-6). The production of IL-6 is, at least partially, genetically determined the single nucleotide polymorphism (SNP) at the promoter (-174G/C) being decisive. Consequently, some studies have demonstrated that the -174G/C genotype...

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Identifiers

PMID: 15664628
DOI: 10.1016/j.mad.2004.10.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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