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Article

A new cell-based assay for measuring the forward mutation rate of HIV-1.

Journal of virological methods - 1 Mar 2005

Huang K J, Wooley D P

Abstract excerpt

Over 20 years into the ever-worsening AIDS pandemic, genetic variation remains the greatest obstacle for treating and preventing HIV-1 infection. Mutation rate assays for HIV-1 have been reported; however, none measure directly the forward mutation rate during replication of the virus in cell culture while still retaining the ability to propagate and further study mutant proviruses. Therefore, the objective of...

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PMID: 15664056
DOI: 10.1016/j.jviromet.2004.11.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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