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Article

Forward mutation rate of human immunodeficiency virus type 1 in a T lymphoid cell line.

AIDS research and human retroviruses - 1 Mar 1996

Mansky L M

Abstract excerpt

An in vivo assay was previously developed for detecting forward mutations in human immunodeficiency virus type 1 (HIV-1) in a single cycle of replication. This system uses the lacZalpha peptide gene as a reporter for mutations, and allows for the rates and types of mutations that occur to be determined. The forward mutation rate for HIV-1 in HeLa cells was found to be 3 x 10(-5) mutations per target base pair per...

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Identifiers

PMID: 8906991
DOI: 10.1089/aid.1996.12.307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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