Alterations of androgen receptor in prostate cancer.

doi:10.1016/j.jsbmb.2004.10.012

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Article

Alterations of androgen receptor in prostate cancer.

The Journal of steroid biochemistry and molecular biology - 1 Nov 2004

Linja Marika J, Visakorpi Tapio

Abstract excerpt

The significance of androgens in the development of prostate cancer has been known for more than half century. During the last decade, a lot of effort has been put to study the significance of the specific nuclear receptor of the hormone, androgen receptor (AR). It has been suggested that polymorphisms, especially the length of CAG repeat in exon 1 of the gene, are associated with the risk of prostate cancer....

Topics

Androgen Antagonists
Drug Resistance, Neoplasm
Gene Amplification
Gene Expression Regulation, Neoplastic
Germ Cells
Humans
Male
Models, Biological
Mutation
Neoplasms, Hormone-Dependent
Polymorphism, Genetic
Prostatic Neoplasms
Receptor, ErbB-2
Receptors, Androgen
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 15663988
DOI: 10.1016/j.jsbmb.2004.10.012

Provenance

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