Article
Role of androgen receptor in prostate cancer.
Asian journal of andrology - 1 Sept 1999
Suzuki H, Ito H
Abstract excerpt
The growth of prostate cancer is sensitive to androgen, and hormonal therapy has been used for treatment of advanced cancer. About 80% of prostate cancers initially respond to hormonal therapy, however, more than half of the responders gradually become resistant to this therapy. Changes in tumors from an androgen-responsive to an androgen-unresponsive state have been widely discussed. Since androgen action is...
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