Article
Expression, structure, and function of androgen receptor in advanced prostatic carcinoma.
The Prostate - 1 Apr 1998
Culig Z, Hobisch A, Hittmair A, Peterziel H, Cato A C, Bartsch G, Klocker H
Abstract excerpt
BACKGROUND: Endocrine therapy for prostate cancer aims to reduce the levels of circulating androgen or to inhibit androgen action by blocking the androgen receptor in the prostate, or both. Studies in various animal and human prostate cancer models suggested that there may be a downregulation of...
Topics
- Androgen Antagonists
- Androgens
- Gene Expression
- Humans
- Male
- Mutation
- Prostatic Neoplasms
- Receptors, Androgen
- Signal Transduction