Article
Androgens, antiandrogens and androgen receptor abnormalities.
European urology - 1 Jan 1996
Kuil C W, Brinkmann A O
Abstract excerpt
Information on the molecular structure of the human androgen receptor has increased insight into the molecular mechanism of action of androgens and antiandrogens. It has also facilitated the study of molecular defects in the androgen receptor gene associated with prostate cancer. Several somatic mutations have been detected in tumour specimens of patients with prostate cancer. Most of the reported mutations are...
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