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Article

Contribution of the androgen receptor to prostate cancer predisposition and progression.

Cancer metastasis reviews - 1 Jan 2001

Buchanan G, Irvine R A, Coetzee G A, Tilley W D

Abstract excerpt

Although prostate cancer is heterogeneous in its etiology and progression, androgen signaling through the androgen receptor (AR) appears to be involved in all aspects of the disease, from initiation to development of treatment resistance. Lifetime exposure to a constitutively more active AR, encoded by AR alleles as defined by two translated polymorphic microsatellites (CAG and GGC), results in a significant...

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Identifiers

PMID: 12085963
DOI: 10.1023/a:1015531326689

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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