Article
[Mutations of the androgen receptor gene a possible role in prostate cancer].
Bulletin du cancer - 1 Feb 1997
Mowszowicz I, Mestayer C
Abstract excerpt
Prostate cancer is the second most frequent cancer in men, and the first after 75 years of age. It is androgen dependent and modifications of the androgen receptor (AR) could therefore be involved in its apparition, progression and evolution towards a stage of androgen independence which always occurs. Mutations of the AR have indeed been described. Some result in a more active receptor (constitutive mutations,...
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