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Article

An autoregulatory circuit for long-range self-organization in Dictyostelium cell populations.

Nature - 20 Jan 2005

Sawai Satoshi, Thomason Peter A, Cox Edward C

Abstract excerpt

Nutrient-deprived Dictyostelium amoebae aggregate to form a multicellular structure by chemotaxis, moving towards propagating waves of cyclic AMP that are relayed from cell to cell. Organizing centres are not formed by founder cells, but are dynamic entities consisting of cores of outwardly rotating spiral waves that self-organize in a homogeneous cell population. Spiral waves are ubiquitously observed in...

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Identifiers

PMID: 15662425
DOI: 10.1038/nature03228

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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