Article
A critical-like collective state leads to long-range cell communication in Dictyostelium discoideum aggregation.
PLoS biology - 1 Apr 2017
De Palo Giovanna, Yi Darvin, Endres Robert G
Abstract excerpt
The transition from single-cell to multicellular behavior is important in early development but rarely studied. The starvation-induced aggregation of the social amoeba Dictyostelium discoideum into a multicellular slug is known to result from single-cell chemotaxis towards emitted pulses of cyclic adenosine monophosphate (cAMP). However, how exactly do transient, short-range chemical gradients lead to coherent...
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