Article
Dissecting cell biology with chemical scalpels.
Current opinion in cell biology - 1 Feb 2005
Hathaway Nathaniel A, King Randall W
Abstract excerpt
Understanding complex cellular processes requires methods for specifically perturbing protein function in a temporally defined fashion. In recent years a variety of chemical tools have been used to study the cytoskeleton and cell division, protein trafficking, and the destruction of proteins by the ubiquitin-proteasome system. The ability to use combinations of reversible inhibitors is proving to be especially...
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