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Targeting and extending the eukaryotic druggable genome with natural products: cytoskeletal targets of natural products

25 Nov 2019

Abstract excerpt

Covering: 2014-2019We review recent progress on natural products that target cytoskeletal components, including microtubules, actin, intermediate filaments, and septins and highlight their demonstrated and potential utility in the treatment of human disease. The anticancer efficacy of microtubule targeted agents identified from plants, microbes, and marine organisms is well documented. We highlight new...

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PMID: 31764930
DOI: 10.1039/c9np00053d

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