Genetic instability of C. elegans comes naturally.

Abstract excerpt

There have been many attempts to measure the genome-wide mutation rate for spontaneous mutations, using measurements of traits in inbred lines in which mutations have accumulated. However, these are likely to miss many small-effect mutations that are important for evolutionary processes. Recently, the genome-wide spontaneous mutation rate in inbred lines of Caenorhabditis elegans was estimated, using DNA...

Topics

• Animals
• Caenorhabditis elegans
• DNA
• Genetics, Population
• Genome
• Models, Genetic
• Mutation
• Phenotype
• Sequence Analysis, DNA