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Article

Skeletal muscle contractile performance and ADP accumulation in adenylate kinase-deficient mice.

American journal of physiology. Cell physiology - 1 Jun 2005

Hancock Chad R, Janssen Edwin, Terjung Ronald L

Abstract excerpt

The production of AMP by adenylate kinase (AK) and subsequent deamination by AMP deaminase limits ADP accumulation during conditions of high-energy demand in skeletal muscle. The goal of this study was to investigate the consequences of AK deficiency (-/-) on adenine nucleotide management and whole muscle function at high-energy demands. To do this, we examined isometric tetanic contractile performance of the...

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Identifiers

PMID: 15659712
DOI: 10.1152/ajpcell.00567.2004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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