Article
Absence of myofibrillar creatine kinase and diaphragm isometric function during repetitive activation.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Apr 1998
LaBella J J, Daood M J, Koretsky A P, Roman B B, Sieck G C, Wieringa B, Watchko J F
Abstract excerpt
Creatine kinase (CK) provides ATP buffering in skeletal muscle and is expressed as 1) cytosolic myofibrillar CK (M-CK) and 2) sarcomeric mitochondrial CK (ScCKmit) isoforms that differ in their subcellular localization. We compared the isometric contractile and fatigue properties of 1) control CK-sufficient (Ctl), 2) M-CK-deficient (M-CK[-/-]), and 3) combined M-CK/ScCKmit-deficient null mutant (CK[-/-])...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
