Article
Endofin recruits clathrin to early endosomes via TOM1.
Journal of cell science - 1 Feb 2005
Seet Li-Fong, Hong Wanjin
Abstract excerpt
TOM1 and its related proteins, TOM1-like1 (TOM1-L1) and TOM1-like2 (TOM1-L2), constitute a subfamily of the VHS domain protein family. We have recently shown that endofin, a FYVE domain protein associated with the early endosome, is able to recruit cytosolic TOM1 onto endosomal membranes. To reveal the biological consequence of endofin-mediated endosomal recruitment of TOM1, we have identified the clathrin heavy...
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