Article
Evolutionary Changes on the Way to Clathrin-Mediated Endocytosis in Animals.
Genome biology and evolution - 12 Feb 2016
Dergai Mykola, Iershov Anton, Novokhatska Olga, Pankivskyi Serhii, Rynditch Alla
Abstract excerpt
Endocytic pathways constitute an evolutionarily ancient system that significantly contributed to the eukaryotic cell architecture and to the diversity of cell type-specific functions and signaling cascades, in particular of metazoans. Here we used comparative proteomic studies to analyze the universal internalization route in eukaryotes, clathrin-mediated endocytosis (CME), to address the issues of how this...
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