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Article

Search for apoptotic nucleases in yeast: role of Tat-D nuclease in apoptotic DNA degradation.

The Journal of biological chemistry - 15 Apr 2005

Qiu Junzhuan, Yoon Jung-Hoon, Shen Binghui

Abstract excerpt

DNA fragmentation/degradation is an important step for apoptosis. However, in unicellular organisms such as yeast, this process has rarely been investigated. In the current study, we revealed eight apoptotic nuclease candidates in Saccharyomyces cerevisiae, analogous to the Caenorhabditis elegans apoptotic nucleases. One of them is Tat-D. Sequence comparison indicates that Tat-D is conserved across kingdoms,...

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PMID: 15657035
DOI: 10.1074/jbc.M413547200

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TAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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