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Article

Cell cycle-dependent regulation of double-strand break repair: a role for the CDK.

Cell cycle (Georgetown, Tex.) - 1 Feb 2005

Aylon Yael, Kupiec Martin

Abstract excerpt

DNA Double-Strand Breaks (DSBs) are dangerous lesions that can lead to genomic instability and to cell death. Eukaryotic cells repair DSBs either by nonhomologous end joining (NHEJ) or by homologous recombination (HR). Recent work has allowed to study the ability of yeast cells to repair a single, chromosomal DSB, at different stages of the cell cycle. Yeast cells repair the broken chromosome during the G(1)...

Topics

Cell Cycle
Cell Cycle Proteins
Chromosome Breakage
Cyclin-Dependent Kinases
DNA
DNA Damage
DNA Repair
DNA, Fungal
G1 Phase
Gene Expression Regulation, Fungal
Genes, Fungal
Genomic Instability

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Recombination, Genetic

Saccharomyces cerevisiae

Source

Identifiers

PMID: 15655342

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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