Article
Cell cycle-dependent regulation of double-strand break repair: a role for the CDK.
Cell cycle (Georgetown, Tex.) - 1 Feb 2005
Aylon Yael, Kupiec Martin
Abstract excerpt
DNA Double-Strand Breaks (DSBs) are dangerous lesions that can lead to genomic instability and to cell death. Eukaryotic cells repair DSBs either by nonhomologous end joining (NHEJ) or by homologous recombination (HR). Recent work has allowed to study the ability of yeast cells to repair a single, chromosomal DSB, at different stages of the cell cycle. Yeast cells repair the broken chromosome during the G(1)...
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