Article
[Gene chip analysis of mutation of HBV-DNA open reading frame].
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology - 1 Dec 2004
Chen Shi-jun, Du Wen-jun, Lu Yan-qin, Xu Wei, An Yong
Abstract excerpt
OBJECTIVE: To detect the mutation of HBV-DNA open reading frame (ORF), provide evidences for clinical diagnosis and treatment. METHODS: By using gene chip technique, HBV-DNA was amplified by PCR, incorporated with fluorescence, hybridized with oligonucleotide to detect the gene sequence of DNA by computer analysis and observe the natural mutation of HBV-DNA ORF. RESULTS: The mutations of HBV-DNA ORF existed...
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