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Article

ARCH domain of XPD, an anchoring platform for CAK that conditions TFIIH DNA repair and transcription activities.

Proceedings of the National Academy of Sciences of the United States of America - 19 Feb 2013

Abdulrahman Wassim, Iltis Izarn, Radu Laura, Braun Cathy, Maglott-Roth Anne, Giraudon Christophe, Egly Jean-Marc, Poterszman Arnaud

Abstract excerpt

The xeroderma pigmentosum group D (XPD) helicase is a subunit of transcription/DNA repair factor, transcription factor II H (TFIIH) that catalyzes the unwinding of a damaged DNA duplex during nucleotide excision repair. Apart from two canonical helicase domains, XPD is composed of a 4Fe-S cluster domain involved in DNA damage recognition and a module of uncharacterized function termed the "ARCH domain." By...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Iron-Sulfur Proteins

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Source

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Identifiers

PMID: 23382212
DOI: 10.1073/pnas.1213981110
PMCID: PMC3581935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ARCH domain of XPD, an anchoring platform for CAK that conditions TFIIH DNA repair and transcription activities.PMID 23382212Read ↗

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