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Article

Vaccination with an inactivated virulent feline immunodeficiency virus engineered to express high levels of Env.

Journal of virology - 1 Feb 2005

Hosie Margaret J, Klein Dieter, Binley James M, Dunsford Thomas H, Jarrett Oswald, Neil James C, Knapp Elzbieta, Giannecchini Simone, Matteucci Donatella, Bendinelli Mauro, Hoxie James A, Willett Brian J

Abstract excerpt

An inactivated virus vaccine was prepared from a pathogenic isolate of feline immunodeficiency virus containing a mutation that eliminated an endocytic sorting signal in the envelope glycoprotein, increasing its expression on virions. Cats immunized with inactivated preparations of this modified virus exhibited strong titers of antibody to Env by enzyme-linked immunosorbent assay. Evidence of protection following...

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Source

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Identifiers

PMID: 15650222
DOI: 10.1128/JVI.79.3.1954-1957.2005
PMCID: PMC544106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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