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Article

Primary malignant lymphoma of the brain: frequent abnormalities and inactivation of p14 tumor suppressor gene.

Cancer science - 1 Jan 2005

Zhang Shu-Jing, Endo Sumio, Saito Takafumi, Kouno Mitsuo, Kuroiwa Toshihiko, Washiyama Kazuo, Kumanishi Toshiro

Abstract excerpt

Ten primary central nervous system lymphomas (PCNSL, brain lymphomas) were examined for p14 gene exon 1beta deletion, mutation and methylation by Southern blot analysis, nucleotide analysis of polymerase chain reaction clones and Southern blot-based methylation assay. In Southern blot analysis, from the signal densities of the hybridized bands and their similarities to those of exons 2 and 3 in our previous...

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Identifiers

PMID: 15649253
DOI: 10.1111/j.1349-7006.2005.00003.x
PMCID: PMC11159332

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Source receipt: pubmed, retrieved 7 Sept 2026.

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