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Article

Intrinsic chemotherapy resistance to the tubulin-binding antimitotic agents in renal cell carcinoma.

International journal of cancer - 20 May 2005

Ferguson Roisean E, Jackson Sharon M, Stanley Anthea J, Joyce Adrian D, Harnden Patricia, Morrison Ewan E, Patel Poulam M, Phillips Roger M, Selby Peter J, Banks Rosamonde E

Abstract excerpt

Renal cancer is one of the most chemoresistant tumor types. Using a panel of 10 established renal cancer cell lines that have not been subjected to prior drug selection, the range of functional resistance phenotypes to the tubulin-binding agents paclitaxel, vinblastine, vincristine and patupilone (epothilone B, EPO906) was determined, together with expression of P-glycoprotein (PgP), multidrug resistance...

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Identifiers

PMID: 15645438
DOI: 10.1002/ijc.20816

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MVP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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