Article
Establishment of in-vitro models of chemotherapy resistance.
Anti-cancer drugs - 1 Aug 2007
Watson Mark B, Lind Michael J, Cawkwell Lynn
Abstract excerpt
Chemotherapy resistance is one of the most prevalent obstacles to the treatment of cancer, resulting in increased mortality and prolonged exposure to cytotoxic agents with no treatment benefit. One of the tools utilized in the study of mechanisms of chemotherapy resistance are established cell lines derived from human neoplasms. These cell lines can be challenged in vitro with controlled chemotherapy doses to...
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