Article
Immunosuppression in renal cancer: differential expression of signal transduction molecules in tumor-infiltrating, near-tumor tissue, and peripheral blood lymphocytes.
Cancer investigation - 1 Jan 2004
Riccobon Angela, Gunelli Roberta, Ridolfi Ruggero, De Paola Franca, Flamini Emanuela, Fiori Massimo, Saltutti Carlo, Petrini Massimiliano, Fiammenghi Laura, Stefanelli Monica, Granato Anna Maria, Cuzzocrea Diego Ettore, Amadori Dino
Abstract excerpt
Alterations in the expression of signal activation molecules, such as the T-cell receptor (TCR) zeta and epsilon chains and p56lck tyrosine kinase, are described in tumor-infiltrating lymphocytes (TIL). The aim of this study was to ascertain if such molecules were present in near-tumor-tissue lymphocytes (NTTL) and peripheral blood lymphocytes (PBL), as well as TIL, of renal cell carcinoma patients, to verify...
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