Article
Cytomegalovirus exposure, immune exhaustion and cancer occurrence in renal transplant recipients.
Transplant international : official journal of the European Society for Organ Transplantation - 1 Sept 2012
Courivaud Cécile, Bamoulid Jamal, Gaugler Béatrice, Roubiou Caroline, Arregui Charlène, Chalopin Jean-Marc, Borg Christophe, Tiberghien Pierre, Woronoff-Lemsi Marie-Christine, Saas Philippe, Ducloux Didier
Abstract excerpt
The role of Cytomegalovirus (CMV) in carcinogenesis is controversial. We studied whether CMV may contribute to cancer occurrence in renal transplant recipients. We studied a prospective cohort of 455 consecutive patients who received a kidney transplant between January 1995 and December 2006. All cancers and types of cancers were assessed. Lymphocyte phenotype and cytokines production were analysed according to...
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