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Article

Simultaneous infiltration of polyfunctional effector and suppressor T cells into renal cell carcinomas.

Cancer research - 1 Nov 2009

Attig Sebastian, Hennenlotter Jörg, Pawelec Graham, Klein Gerd, Koch Sven D, Pircher Hanspeter, Feyerabend Susan, Wernet Dorothee, Stenzl Arnulf, Rammensee Hans-Georg, Gouttefangeas Cécile

Abstract excerpt

Renal cell carcinoma is frequently infiltrated by cells of the immune system. This makes it important to understand interactions between cancer cells and immune cells so they can be manipulated to bring clinical benefit. Here, we analyze subsets and functions of T lymphocytes infiltrating renal cell tumors directly ex vivo following mechanical disaggregation and without any culture step. Subpopulations of memory...

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Source

Identifiers

PMID: 19843860
DOI: 10.1158/0008-5472.CAN-09-0852

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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