Article
Natural Killer Lymphocytes Are Dysfunctional in Kidney Transplant Recipients on Diagnosis of Cancer.
Transplantation - 1 Nov 2015
Peraldi Marie-Noëlle, Berrou Jeannig, Venot Marion, Chardiny Victor, Durrbach Antoine, Vieillard Vincent, Debré Patrice, Charron Dominique, Suberbielle Caroline, Chevret Sylvie, Glotz Denis, Dulphy Nicolas, Toubert Antoine
Abstract excerpt
BACKGROUND: The incidence of cancer is increased after solid organ transplantation. Natural killer (NK) cells are key effectors of the tumor immune response. METHODS: We conducted a cross sectional multicentre matched case-control study including 42 kidney transplant recipients (KTRs) on diagnosis of cancer and 41 KTRs without cancer. Extensive phenotyping of NK cells populations and functional tests of NK cells...
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