Article
Association of SLC11A1 (NRAMP1) with persistent oligoarticular and polyarticular rheumatoid factor-negative juvenile idiopathic arthritis in Finnish patients: haplotype analysis in Finnish families.
Arthritis and rheumatism - 1 Jan 2005
Runstadler Jonathan A, Säilä Hanna, Savolainen Anneli, Leirisalo-Repo Marjatta, Aho Kimmo, Tuomilehto-Wolf Eva, Tuomilehto Jaakko, Seldin Michael F
Abstract excerpt
OBJECTIVE: The SLC11A1 (formerly called NRAMP1) gene is important in natural resistance to a variety of intracellular infections mediated by macrophages and has been proposed as a candidate gene for autoimmune disease susceptibility. The aim of this study was to examine susceptibility in Finnish patients with persistent oligoarticular and polyarticular rheumatoid factor (RF)-negative juvenile idiopathic arthritis...
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