Article
Identification of a novel candidate locus for juvenile idiopathic arthritis at 14q13.2 in the Latvian population by association analysis with microsatellite markers.
DNA and cell biology - 1 Sept 2010
Sjakste Tatjana, Trapina Ilva, Rumba-Rozenfelde Ingrida, Lunin Roman, Sugoka Olga, Sjakste Nikolajs
Abstract excerpt
To identify novel juvenile idiopathic arthritis (JIA) susceptibility loci, a 270 kb genomic region encompassing FAM177A1, KIAA0391, and PSMA6 genes was genotyped in 97 oligoarthritis (JIoA) and 50 polyarthritis (JIpA) patients and 230 individuals without autoimmune disorders by five microsatellites (MS) previously described as HSMS markers of the 14q13.2 region. Direct sequencing revealed two variable components...
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