Article
Positive association of SLC26A2 gene polymorphisms with susceptibility to systemic-onset juvenile idiopathic arthritis.
Arthritis and rheumatism - 1 Apr 2007
Lamb Rebecca, Thomson Wendy, Ogilvie Emma M, Donn Rachelle
Abstract excerpt
OBJECTIVE: To investigate SLC26A2, the gene that causes diastrophic dysplasia, in juvenile idiopathic arthritis (JIA). METHODS: Nine polymorphisms across the SLC26A2 gene locus were investigated using MassArray genotyping in 826 UK Caucasian JIA cases and 617 ethnically matched healthy controls. RESULTS: Significant associations between multiple single-nucleotide polymorphisms (SNPs) across SLC26A2 and...
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