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Article

Genes involved in formation and attachment of a two-carbon chain as a component of eurekanate, a branched-chain sugar moiety of avilamycin A.

Applied and environmental microbiology - 1 Jan 2005

Treede Irina, Hauser Gerd, Mühlenweg Agnes, Hofmann Carsten, Schmidt Maraike, Weitnauer Gabriele, Glaser Steffen, Bechthold Andreas

Abstract excerpt

Eurekanate belongs to the important class of branched-chain carbohydrates present in a wide variety of natural sources. It is a component of avilamycin A, a potent inhibitor of bacterial protein synthesis targeting the 50S ribosomal subunit. The present work provides experimental proof for the function of two genes of the avilamycin biosynthetic gene cluster, aviB1 and aviO2, that are both involved in avilamycin...

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Identifiers

PMID: 15640214
DOI: 10.1128/AEM.71.1.400-406.2005
PMCID: PMC544256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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