Article
Isolation and characterization of a mutant of the marine bacterium Alcanivorax borkumensis SK2 defective in lipid biosynthesis.
Applied and environmental microbiology - 1 May 2010
Manilla-Pérez Efraín, Lange Alvin Brian, Hetzler Stephan, Wältermann Marc, Kalscheuer Rainer, Steinbüchel Alexander
Abstract excerpt
In many microorganisms, the key enzyme responsible for catalyzing the last step in triacylglycerol (TAG) and wax ester (WE) biosynthesis is an unspecific acyltransferase which is also referred to as wax ester synthase/acyl coenzyme A (acyl-CoA):diacylglycerol acyltransferase (WS/DGAT; AtfA). The importance and function of two AtfA homologues (AtfA1 and AtfA2) in the biosynthesis of TAGs and WEs in the...
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