Article
A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis.
Proceedings of the National Academy of Sciences of the United States of America - 18 Aug 1998
Takahashi S, Kuzuyama T, Watanabe H, Seto H
Abstract excerpt
Several eubacteria including Esherichia coli use an alternative nonmevalonate pathway for the biosynthesis of isopentenyl diphosphate instead of the ubiquitous mevalonate pathway. In the alternative pathway, 2-C-methyl-D-erythritol or its 4-phosphate, which is proposed to be formed from 1-deoxy-D...
Topics
- Aldose-Ketose Isomerases
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- DNA Primers
- Erythritol
- Escherichia coli
- Genes, Bacterial
- Genetic Complementation Test
- Hemiterpenes
- Mevalonic Acid
- Molecular Sequence Data
- Multienzyme Complexes