Article
Genetic analysis of the balhimycin (vancomycin-type) oxygenase genes.
Journal of biotechnology - 5 Aug 2006
Stegmann Evi, Pelzer Stefan, Bischoff Daniel, Puk Oliver, Stockert Sigrid, Butz Diane, Zerbe Katja, Robinson John, Süssmuth Roderich D, Wohlleben Wolfgang
Abstract excerpt
In the balhimycin biosynthesis three oxygenases OxyA, OxyB and OxyC are responsible for the oxidative phenol coupling reactions, which lead to the ring-closures between the aromatic amino acid side chains in the heptapeptide aglycone. These ring-closures constrain the peptide backbone into the cu...
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