A mechanism for valine-resistant growth of Escherichia coli K-12 supported by the valine-sensitive acetohydroxy acid synthase IV activity from ilvJ662.

doi:10.1016/0300-9084(93)90125-c

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Article

A mechanism for valine-resistant growth of Escherichia coli K-12 supported by the valine-sensitive acetohydroxy acid synthase IV activity from ilvJ662.

Biochimie - 1 Jan 1993

Jackson J H, Herring P A, Patterson E B, Blatt J M

Abstract excerpt

Acetohydroxy acid synthase (EC 4.1.3.18; AHAS) isozymes I and III are expressed in Escherichia coli strain K-12 and, when inhibited by L-valine, cannot support cell growth. AHAS IV, expressed from mutation at ilvJ662, exhibits valine-sensitivity similar to that of AHAS III, yet AHAS IV does suppo...

Topics

Acetolactate Synthase
Butyrates
Cell Division
Culture Media
Escherichia coli
Feedback
Isoenzymes
Kinetics
Mutation
Valine

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