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Article

Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity.

Proceedings of the National Academy of Sciences of the United States of America - 11 Sept 2007

Van Damme Philip, Bogaert Elke, Dewil Maarten, Hersmus Nicole, Kiraly Dora, Scheveneels Wendy, Bockx Ilse, Braeken Dries, Verpoorten Nathalie, Verhoeven Kristien, Timmerman Vincent, Herijgers Paul, Callewaert Geert, Carmeliet Peter, Van Den Bosch Ludo, Robberecht Wim

Abstract excerpt

Influx of Ca(2+) ions through alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors contributes to neuronal damage in stroke, epilepsy, and neurodegenerative disorders such as ALS. The Ca(2+) permeability of AMPA receptors is largely determined by the glutamate receptor 2 (Glu...

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Identifiers

PMID: 17804792
DOI: 10.1073/pnas.0705046104
PMCID: PMC1976195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17804792-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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